Radial propagation of muscle action potential along the tubular system examined by potential-sensitive dyes.

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Radial propagation of muscle action potential along the tubular system examined by potential-sensitive dyes

Isolated single (Xenopus) muscle fibers were stained with a non-permeant potential-probing dye, merocyanine rhodanine (WW375) or merocyanine oxazolone (NK2367). When the fiber was massively stimulated, an absorption change (wave a), which seemed to reflect the action potential, occurred. Simultaneous recording of optical changes and intracellular action potentials revealed that the time-course ...

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The Different Mechanisms of Action Potential Propagation in the Heart

It was thought previously that cardiac muscle gap junctions provide low-resistance connections between cells and permit the local-circuit current to flow. Some evidences show that myocardial cells may not require low-resistance connections for successful propagation of the action potential (AP). It seems that some other types of mechanisms must be involved in AP propagation. In this article, we...

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The Different Mechanisms of Action Potential Propagation in the Heart

It was thought previously that cardiac muscle gap junctions provide low-resistance connections between cells and permit the local-circuit current to flow. Some evidences show that myocardial cells may not require low-resistance connections for successful propagation of the action potential (AP). It seems that some other types of mechanisms must be involved in AP propagation. In this article, we...

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Action potentials of isolated single muscle fibers recorded by potential-sensitive dyes

Light transmission changes upon massive stimulation of single muscle fibers of Xenopus were studied with the potential-sensitive nonpermeant dyes, merocyanine rhodanine (WW375) and merocyanine oxazolone (NK2367). Upon stimulation an absorption change (wave a) occurred, which probably represents the sum of action potentials in the transverse tubules and surface membrane. In WW375-stained fibers ...

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[Brief letters to the Editor that make specific scientific reference to papers published previously in THE JOURNAL OF GENERAL PHYSIOLOGY are invited. Receipt of such letters will be acknowledged, and those containing pertinent scientific comments and scientific criticisms will be published.] Dear Sir: Costantin (1970) controlled the potential across the surface membrane of a skeletal muscle fib...

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ژورنال

عنوان ژورنال: Journal of General Physiology

سال: 1980

ISSN: 0022-1295,1540-7748

DOI: 10.1085/jgp.76.6.751